MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP005982

Ontology/Pathway Information

Entrez Gene ID80270
Gene Namehydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Gene Symbol HSD3B7
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0003854 NAS:UniProtKBF3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0047016 IEA:UniProtKB-ECFcholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
GO:0006699 TAS:UniProtKBPbile acid biosynthetic process
GO:0008206 TAS:ReactomePbile acid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11040Bile acid and bile salt metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11054Synthesis of bile acids and bile salts
REACT_11053Synthesis of bile acids and bile salts via 24-hydroxycholesterol
REACT_11048Synthesis of bile acids and bile salts via 27-hydroxycholesterol
REACT_11041Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
SMP Pathway Links
SMP IDDescription
SMP0072027-Hydroxylase Deficiency
SMP00035Bile Acid Biosynthesis
SMP00315Cerebrotendinous Xanthomatosis (CTX)
SMP00314Congenital Bile Acid Synthesis Defect Type II
SMP00318Congenital Bile Acid Synthesis Defect Type III
SMP00317Familial Hypercholanemia (FHCA)
SMP00316Zellweger Syndrome
  logo