MGP Database

MGP006003

Ontology/Pathway Information

Entrez Gene ID80781
Gene Namecollagen, type XVIII, alpha 1
Gene Symbol COL18A1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005604 IEA:EnsemblCbasement membrane
GO:0005581 TAS:ProtIncCcollagen trimer
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0031012 IDA:UniProtKBCextracellular matrix
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0042802 IPI:IntActFidentical protein binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0005198 IEA:InterProFstructural molecule activity
GO:0001525 IEA:EnsemblPangiogenesis
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0001886 IEA:EnsemblPendothelial cell morphogenesis
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0008285 TAS:ProtIncPnegative regulation of cell proliferation
GO:0009887 TAS:ProtIncPorgan morphogenesis
GO:0030335 IEA:EnsemblPpositive regulation of cell migration
GO:0008284 IEA:EnsemblPpositive regulation of cell proliferation
GO:2000353 IEA:EnsemblPpositive regulation of endothelial cell apoptotic process
GO:0042493 IEA:EnsemblPresponse to drug
GO:0051599 IEA:EnsemblPresponse to hydrostatic pressure
GO:0007601 TAS:ProtIncPvisual perception
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118682Activation of Matrix Metalloproteinases
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_121139Collagen biosynthesis and modifying enzymes
REACT_150401Collagen degradation
REACT_120729Collagen formation
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
REACT_13552Integrin cell surface interactions
REACT_169262Laminin interactions
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