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MGP006012

Record overview

MGPD IDMGP006012
Gene ID81027
SpeciesHomo sapiens (Human)
Gene Nametubulin, beta 1 class VI
Gene Symbol TUBB1
Alternate namestubulin beta-1 chain; beta tubulin 1, class VI; class VI beta-tubulin;
Chromosome20
Map Location20q13.32
SummaryThis gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]
OrthologsView orthologs and multiple alignments for TUBB1

Proteins

tubulin beta-1 chain
Refseq ID:NP_110400
Protein GI:13562114
UniProt ID:Q9H4B7
mRNA ID:NM_030773
Length:451
RefSeq Status:
MREIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGRKYVPRAVLVDLEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNN
WAKGHYTEGAELIENVLEVVRHESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENADACF
CIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTM
AACDLRRGRYLTVACIFRGKMSTKEVDQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPPRGLSMAATFIGNNTAIQEIFNRVSEHFSAMFKRKAFVHWYTS
EGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEEDEEVTEEAEMEPEDKGH
 
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