MGP Database

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MGP006091

UniProt Annotations

Entry Information
Gene Namesolute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
Protein EntryORNT2_HUMAN
UniProt IDQ9BXI2
SpeciesHuman
Comments
Comment typeDescription
FunctionOrnithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
PolymorphismVariant Cys-159 has a reduced ornithine transport activity, while variant Gly-181 has an increased activity.
SimilarityBelongs to the mitochondrial carrier (TC 2.A.29) family. {ECO:0000305}.
SimilarityContains 3 Solcar repeats. {ECO:0000255|PROSITE- ProRule:PRU00282}.
Subcellular LocationMitochondrion inner membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in liver, kidney, pancreas and cultured fibroblasts.
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