MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP006322

Ontology/Pathway Information

Entrez Gene ID112399
Gene Nameegl-9 family hypoxia-inducible factor 3
Gene Symbol EGLN3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005506 IEA:InterProFiron ion binding
GO:0031418 IEA:UniProtKB-KWFL-ascorbic acid binding
GO:0016706 IDA:MGIFoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031545 IDA:FlyBaseFpeptidyl-proline 4-dioxygenase activity
GO:0006919 IEP:UniProtKBPactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006915 IEP:UniProtKBPapoptotic process
GO:0006974 IEA:UniProtKB-KWPcellular response to DNA damage stimulus
GO:0071456 TAS:ReactomePcellular response to hypoxia
GO:0018401 IDA:FlyBasePpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0018126 IDA:UniProtKBPprotein hydroxylation
GO:0042127 IEP:UniProtKBPregulation of cell proliferation
GO:0043523 ISS:UniProtKBPregulation of neuron apoptotic process
GO:0061418 TAS:ReactomePregulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0001666 IEP:UniProtKBPresponse to hypoxia
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120956Cellular responses to stress
REACT_121311Cellular response to hypoxia
REACT_120916Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
REACT_120815Regulation of Hypoxia-inducible Factor (HIF) by oxygen
  logo