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MGP006323

Record overview

MGPD IDMGP006323
Gene ID112724
SpeciesHomo sapiens (Human)
Gene Nameretinol dehydrogenase 13 (all-trans/9-cis)
Gene Symbol RDH13
SynonymsSDR7C3;
Alternate namesretinol dehydrogenase 13; retinol dehydrogenase 13 (all-trans and 9-cis); short chain dehydrogenase/reductase family 7C, member 3;
Chromosome19
Map Location19q13.42
EC Number1.1.1.-;
SummaryThis gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
OrthologsView orthologs and multiple alignments for RDH13

Proteins

retinol dehydrogenase 13 isoform 1 precursor
Refseq ID:NP_001139443
Protein GI:225579078
UniProt ID:Q8NBN7
mRNA ID:NM_001145971
Length:331
RefSeq Status:
MSRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLAS
LKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAY
CQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADVSGKYFDGLKQKAPAPEA
EDEEVARRLWAESARLVGLEAPSVREQPLPR
 
sig_peptide: 1..16
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1649
peptide sequence: 
MSRYLLPLSALGTVAG
 
retinol dehydrogenase 13 isoform 2
Refseq ID:NP_612421
Protein GI:19923931
UniProt ID:Q8NBN7
mRNA ID:NM_138412
Length:260
RefSeq Status:
MEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIIN
LSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQPS
TYLAVAEELADVSGKYFDGLKQKAPAPEAEDEEVARRLWAESARLVGLEAPSVREQPLPR
 
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