MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP006338

Record overview

MGPD IDMGP006338
Gene ID113612
SpeciesHomo sapiens (Human)
Gene Namecytochrome P450, family 2, subfamily U, polypeptide 1
Gene Symbol CYP2U1
SynonymsSPG49; SPG56; P450TEC;
Alternate namescytochrome P450 2U1; spastic paraplegia 49;
Chromosome4
Map Location4q25
EC Number1.14.14.1;
SummaryThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CYP2U1

Proteins

cytochrome P450 2U1
Refseq ID:NP_898898
Protein GI:34098959
UniProt ID:Q7Z449
mRNA ID:NM_183075
Length:544
RefSeq Status:
MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSV
IGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKII
EEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKK
IIKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQM
PYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMEL
FLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR
 
  logo