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MGP006439

Record overview

MGPD IDMGP006439
Gene ID123099
SpeciesHomo sapiens (Human)
Gene Namedelta(4)-desaturase, sphingolipid 2
Gene Symbol DEGS2
SynonymsDES2; FADS8; C14orf66;
Alternate namessphingolipid delta(4)-desaturase/C4-hydroxylase DES2; DEGS2; degenerative spermatocyte homolog 2, lipid desaturase; dihydroceramide desaturase 2; sphingolipid C4-hydroxylase/delta 4-desaturase; sphingolipid delta 4 desaturase/C-4 hydroxylase; sphingolipid delta(4)-desaturase 2;
Chromosome14
Map Location14q32.2
EC Number1.-.-.-
SummaryThis gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008]
OrthologsView orthologs and multiple alignments for DEGS2

Proteins

sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
Refseq ID:NP_996801
Protein GI:207113139
UniProt ID:Q6QHC5
mRNA ID:NM_206918
Length:323
RefSeq Status:
MGNSASRSDFEWVYTDQPHTQRRKEILAKYPAIKALMRPDPRLKWAVLVLVLVQMLACWLVRGLAWRWLLFWAYAFGGCVNHSLTLAIHDISHNAAFGTG
RAARNRWLAVFANLPVGVPYAASFKKYHVDHHRYLGGDGLDVDVPTRLEGWFFCTPARKLLWLVLQPFFYSLRPLCVHPKAVTRMEVLNTLVQLAADLAI
FALWGLKPVVYLLASSFLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHVEHHDFPSIPGYNLPLVRKIAPEYYDHLPQHHSWVKVLWDF
VFEDSLGPYARVKRVYRLAKDGL
 
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