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MGP006521

Record overview

MGPD IDMGP006521
Gene ID132158
SpeciesHomo sapiens (Human)
Gene Nameglycerate kinase
Gene Symbol GLYCTK
SynonymsHBEBP2; HBEBP4; HBeAgBP4A;
Alternate namesglycerate kinase; HBeAg binding protein 4; HBeAg-binding protein 2;
Chromosome3
Map Location3p21.1
EC Number2.7.1.31
SummaryThis locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
OrthologsView orthologs and multiple alignments for GLYCTK

Proteins

glycerate kinase isoform 1
Refseq ID:NP_660305
Protein GI:31543063
UniProt ID:Q8IVS8
mRNA ID:NM_145262
Length:523
RefSeq Status:
MAAALQVLPRLARAPLHPLLWRGSVARLASSMALAEQARQLFESAVGAVLPGPMLHRALSLDPGGRQLKVRDRNFQLRQNLYLVGFGKAVLGMAAAAEEL
LGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALRAALAIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTR
LLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVVSLILSDVVGDPVEVIASGPTVASSHNVQDCLHILNRYGLRAALPRSVKTVLSRADSDPHGPHT
CGHVLNVIIGSNVLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLTPSMAGASVEEDAQLHELAAELQIPDLQLEEALETMAWGRG
PVCLLAGGEPTVQLQGSGRGGRNQELALRVGAELRRWPLGPIDVLFLSGGTDGQDGPTEAAGAWVTPELASQAAAEGLDIATFLAHNDSHTFFCCLQGGA
HLLHTGMTGTNVMDTHLLFLRPR
 
glycerate kinase isoform 2
Refseq ID:NP_001138423
Protein GI:222418771
UniProt ID:Q8IVS8
mRNA ID:NM_001144951
Length:234
RefSeq Status:
MAAALQVLPRLARAPLHPLLWRGSVARLASSMALAEQARQLFESAVGAVLPGPMLHRALSLDPGGRQLKVRDRNFQLRQNLYLVGFGKAVLGMAAAAEEL
LGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALRAALAIQQLAEGLTADDLLLVLISGGEPHPVRCGGGPCGGDCQWPHRG
QFPQCARLPAYPQSLRPPCSPATFCEDCAVSGRL
 
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