MGP Database

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MGP006597

UniProt Annotations

Entry Information
Gene Nameamidohydrolase domain containing 1
Protein EntryHUTI_HUMAN
UniProt IDQ96NU7
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity(S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4- yl)propanoate + H(2)O = N-formimidoyl-L-glutamate + H(+).
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250}; Note=Binds 1 zinc or iron ion per subunit. {ECO:0000250};
PathwayAmino-acid degradation; L-histidine degradation into L- glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.
Sequence CautionSequence=BAD38660.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
SimilarityBelongs to the HutI family. {ECO:0000305}.
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