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MGP006740

Record overview

MGPD IDMGP006740
Gene ID196883
SpeciesHomo sapiens (Human)
Gene Nameadenylate cyclase 4
Gene Symbol ADCY4
SynonymsAC4;
Alternate namesadenylate cyclase type 4; ATP pyrophosphate-lyase 4; adenylate cyclase type IV; adenylyl cyclase 4;
Chromosome14
Map Location14q12
SummaryThis gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
OrthologsView orthologs and multiple alignments for ADCY4

Proteins

adenylate cyclase type 4
Refseq ID:NP_640340
Protein GI:24497587
UniProt ID:Q8NFM4
mRNA ID:NM_139247
Length:1077
RefSeq Status:
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVAL
LALGHAFLFTGGVVSAWDQVSYFLFVIFTAYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVLFLCGNVAGVYHKALMERALR
ATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHME
AGGVPGRVHITGATLALLAGAYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGLKMRPSLLMTRYLESWGAAKPFAHLSHGDSP
VSTSTPLPEKTLASFSTQWSLDRSRTPRGLDDELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI
IQMLVTNRPPALAITYSITFLLFLLILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRPGLRIALGTATILLVFAMAITSLFFFPTSSDCPFQAPNVSS
MISNLSWELPGSLPLISVPYSMHCCTLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSECLIVRLYLGPLDSRPGVLKEPKLMGAISFFIFF
FTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR
LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQ
KPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG
 
adenylate cyclase type 4
Refseq ID:NP_001185497
Protein GI:310832386
UniProt ID:Q8NFM4
mRNA ID:NM_001198568
Length:1077
RefSeq Status:
Protein sequence is identical to GI:24497587 (mRNA isoform)
 
adenylate cyclase type 4
Refseq ID:NP_001185521
Protein GI:310832384
UniProt ID:Q86TZ7
mRNA ID:NM_001198592
Length:1077
RefSeq Status:
Protein sequence is identical to GI:24497587 (mRNA isoform)
 
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