MGP Database

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MGP006751

Ontology/Pathway Information

Entrez Gene ID200576
Gene Namephosphoinositide kinase, FYVE finger containing
Gene Symbol PIKFYVE
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0031410 IEA:EnsemblCcytoplasmic vesicle
GO:0005829 IEA:EnsemblCcytosol
GO:0031901 IDA:UniProtKBCearly endosome membrane
GO:0010008 IDA:UniProtKBCendosome membrane
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0031902 TAS:ReactomeClate endosome membrane
GO:0045121 IDA:HGNCCmembrane raft
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0012506 IEA:EnsemblCvesicle membrane
GO:0000285 IEA:UniProtKB-ECF1-phosphatidylinositol-3-phosphate 5-kinase activity
GO:0016308 TAS:HGNCF1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0043813 TAS:ReactomeFphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
GO:0008270 IEA:EnsemblFzinc ion binding
GO:0044267 IEA:InterProPcellular protein metabolic process
GO:0035556 IEA:EnsemblPintracellular signal transduction
GO:0032288 IEA:EnsemblPmyelin assembly
GO:0036092 TAS:GOCPphosphatidylinositol-3-phosphate biosynthetic process
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0046854 TAS:GOCPphosphatidylinositol phosphorylation
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0034504 IMP:UniProtKBPprotein localization to nucleus
GO:0042147 IMP:UniProtKBPretrograde transport, endosome to Golgi
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_121175PI Metabolism
REACT_120756Synthesis of PIPs at the early endosome membrane
REACT_120836Synthesis of PIPs at the Golgi membrane
REACT_120918Synthesis of PIPs at the late endosome membrane
SMP Pathway Links
SMP IDDescription
SMP00011Inositol Metabolism
SMP00582Joubert syndrome
SMP00463Phosphatidylinositol Phosphate Metabolism
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