MGP Database

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MGP006913

UniProt Annotations

Entry Information
Gene Nameheparan sulfate 6-O-sulfotransferase 3
Protein EntryH6ST3_HUMAN
UniProt IDQ8IZP7
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 6-sulfate.
Function6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
SimilarityBelongs to the sulfotransferase 6 family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
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