MGP Database

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MGP007046

Record overview

MGPD IDMGP007046
Gene ID347733
SpeciesHomo sapiens (Human)
Gene Nametubulin, beta 2B class IIb
Gene Symbol TUBB2B
SynonymsPMGYSA; bA506K6.1;
Alternate namestubulin beta-2B chain; class II beta-tubulin isotype; class IIb beta-tubulin; tubulin, beta polypeptide paralog;
Chromosome6
Map Location6p25
SummaryThe protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]
OrthologsView orthologs and multiple alignments for TUBB2B

Proteins

tubulin beta-2B chain
Refseq ID:NP_821080
Protein GI:29788768
UniProt ID:Q9BVA1
mRNA ID:NM_178012
Length:445
RefSeq Status:
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA
 
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