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MGP007053

Record overview

MGPD IDMGP007053
Gene ID349565
SpeciesHomo sapiens (Human)
Gene Namenicotinamide nucleotide adenylyltransferase 3
Gene Symbol NMNAT3
SynonymsPNAT3; FKSG76; PNAT-3;
Alternate namesnicotinamide mononucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NaMN adenylyltransferase 3; nicotinate-nucleotide adenylyltransferase 3; pyridine nucleotide adenylyltransferase 3;
Chromosome3
Map Location3q23
EC Number2.7.7.18
SummaryThis gene encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. These enzymes use ATP to catalyze the synthesis of nicotinamide adenine dinucleotide or nicotinic acid adenine dinucleotide from nicotinamide mononucleotide or nicotinic acid mononucleotide, respectively. The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
OrthologsView orthologs and multiple alignments for NMNAT3

Proteins

nicotinamide mononucleotide adenylyltransferase 3 isoform 1
Refseq ID:NP_835471
Protein GI:30039706
UniProt ID:Q96T66
mRNA ID:NM_178177
Length:215
RefSeq Status:
MYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKALFSTPAAVPELKLLCGAD
VLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGS
TWKGKSTQSTEGKTS
 
nicotinamide mononucleotide adenylyltransferase 3 isoform 2
Refseq ID:NP_001186976
Protein GI:318068039
UniProt ID:Q96T66
mRNA ID:NM_001200047
Length:163
RefSeq Status:
MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTAVPELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNI
HLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWKGKSTQSTEGKTS
 
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