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MGP007258

UniProt Annotations

Entry Information
Gene Nameglutathione S-transferase theta 2B (gene/pseudogene)
Protein EntryGSTT2_HUMAN
UniProt IDP0CG30
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityRX + glutathione = HX + R-S-glutathione.
FunctionConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
SimilarityBelongs to the GST superfamily. Theta family. {ECO:0000305}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SimilarityContains 1 GST N-terminal domain. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer. {ECO:0000269|PubMed:9551553}.
Tissue SpecificityExpressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells. {ECO:0000269|PubMed:8761485}.
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