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MGP007270

Record overview

MGPD IDMGP007270
Gene ID729238
SpeciesHomo sapiens (Human)
Gene Namesurfactant protein A2
Gene Symbol SFTPA2
SynonymsPSAP; PSPA; SP-A; SPA2; PSP-A; SFTP1; SPAII; COLEC5; SFTPA2B;
Alternate namespulmonary surfactant-associated protein A2; 35 kDa pulmonary surfactant-associated protein; alveolar proteinosis protein; collectin 5; surfactant, pulmonary-associated protein A2A;
Chromosome10
Map Location10q22.3
SummaryThis gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009]
OrthologsView orthologs and multiple alignments for SFTPA2

Proteins

pulmonary surfactant-associated protein A2 precursor
Refseq ID:NP_001092138
Protein GI:148886696
UniProt ID:Q8IWL1
mRNA ID:NM_001098668
Length:248
RefSeq Status:
MWLCPLALTLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPMGPPGETPCPPGNNGLPGAPGVPGERGEKGEAGERGPPGLP
AHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRY
SDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1946
peptide sequence: 
MWLCPLALTLILMAASGAA
 
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