MGP Database

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MGP007281

Ontology/Pathway Information

Entrez Gene ID100137049
Gene Namephospholipase A2, group IVB (cytosolic)
Gene Symbol PLA2G4B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:UniProtKBCcytosol
GO:0031901 IEA:UniProtKB-SubCellCearly endosome membrane
GO:0005576 TAS:UniProtKBCextracellular region
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0047498 IDA:UniProtKBFcalcium-dependent phospholipase A2 activity
GO:0005544 NAS:UniProtKBFcalcium-dependent phospholipid binding
GO:0005509 NAS:UniProtKBFcalcium ion binding
GO:0004622 NAS:UniProtKBFlysophospholipase activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0019369 NAS:UniProtKBParachidonic acid metabolic process
GO:0019722 NAS:UniProtKBPcalcium-mediated signaling
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0046475 IDA:UniProtKBPglycerophospholipid catabolic process
GO:0006954 NAS:UniProtKBPinflammatory response
GO:0007567 NAS:UniProtKBPparturition
GO:0006654 TAS:ReactomePphosphatidic acid biosynthetic process
GO:0036151 TAS:ReactomePphosphatidylcholine acyl-chain remodeling
GO:0036152 TAS:ReactomePphosphatidylethanolamine acyl-chain remodeling
GO:0036148 TAS:ReactomePphosphatidylglycerol acyl-chain remodeling
GO:0036150 TAS:ReactomePphosphatidylserine acyl-chain remodeling
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120829Acyl chain remodelling of PC
REACT_121369Acyl chain remodelling of PE
REACT_121324Acyl chain remodelling of PG
REACT_121384Acyl chain remodelling of PS
REACT_121401Glycerophospholipid biosynthesis
REACT_120977Hydrolysis of LPC
REACT_18368IRE1alpha activates chaperones
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_120870Phospholipid metabolism
REACT_120906Synthesis of PA
REACT_18356Unfolded Protein Response (UPR)
REACT_18273XBP1(S) activates chaperone genes
SMP Pathway Links
SMP IDDescription
SMP00710Acetaminophen Action Pathway
SMP00083Acetylsalicylic Acid Action Pathway
SMP00018Alpha Linolenic Acid and Linoleic Acid Metabolism
SMP00692Antipyrine Action Pathway
SMP00693Antrafenine Action Pathway
SMP00075Arachidonic Acid Metabolism
SMP00102Bromfenac Action Pathway
SMP00694Carprofen Action Pathway
SMP00096Celecoxib Action Pathway
SMP00093Diclofenac Action Pathway
SMP00289Diflunisal Action Pathway
SMP00084Etodolac Action Pathway
SMP00695Etoricoxib Action Pathway
SMP00696Fenoprofen Action Pathway
SMP00697Flurbiprofen Action Pathway
SMP00086Ibuprofen Action Pathway
SMP00104Indomethacin Action Pathway
SMP00085Ketoprofen Action Pathway
SMP00098Ketorolac Action Pathway
SMP00353Leukotriene C4 Synthesis Deficiency
SMP00700Lornoxicam Action Pathway
SMP00699Lumiracoxib Action Pathway
SMP00698Magnesium salicylate Action Pathway
SMP00109Mefenamic Acid Action Pathway
SMP00106Meloxicam Action Pathway
SMP00114Nabumetone Action Pathway
SMP00120Naproxen Action Pathway
SMP00702Nepafenac Action Pathway
SMP00113Oxaprozin Action Pathway
SMP00701Phenylbutazone Action Pathway
SMP00025Phospholipid Biosynthesis
SMP00077Piroxicam Action Pathway
SMP00087Rofecoxib Action Pathway
SMP00708Salicylate-sodium Action Pathway
SMP00709Salicylic Acid Action Pathway
SMP00707Salsalate Action Pathway
SMP00094Sulindac Action Pathway
SMP00101Suprofen Action Pathway
SMP00706Tenoxicam Action Pathway
SMP00705Tiaprofenic Acid Action Pathway
SMP00704Tolmetin Action Pathway
SMP00703Trisalicylate-choline Action Pathway
SMP00116Valdecoxib Action Pathway
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