MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP007296

UniProt Annotations

Entry Information
Gene NameNT5C1B-RDH14 readthrough
Protein Entry
UniProt ID
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=4; Name=1; Synonyms=CN-Ib alpha; IsoId=Q96P26-1; Sequence=Displayed; Name=2; IsoId=Q96P26-2; Sequence=VSP_010201; Note=No experimental confirmation available.; Name=3; IsoId=Q96P26-3; Sequence=VSP_010202; Note=No experimental confirmation available.; Name=4; IsoId=Q96P26-4; Sequence=VSP_010203; Note=No experimental confirmation available.;
Catalytic ActivityA 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Enzyme RegulationActivated by ADP. {ECO:0000250}.
FunctionDephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity). {ECO:0000250}.
Sequence CautionSequence=AAK39108.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAK83285.1; Type=Frameshift; Positions=320; Evidence={ECO:0000305}; Sequence=BAC04103.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAC44363.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the 5'-nucleotidase type 3 family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
Tissue SpecificityHighly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung. {ECO:0000269|PubMed:11690631}.
  logo