Summary of Study ST000785
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000571. The data can be accessed directly via it's Project DOI: 10.21228/M8VM2M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000785 |
Study Title | Pharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock |
Study Type | multiple timepoints; patients with severe sepsis or septic shock |
Study Summary | phase I study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
Institute | University of Michigan |
Department | Clinical Pharmacy |
Laboratory | The NMR Metabolomics Laboratory (Stringer) |
Last Name | Stringer |
First Name | Kathleen |
Address | University Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105 |
NMRmetabolomics@umich.edu | |
Phone | none |
Submit Date | 2016-12-08 |
Num Groups | 2 |
Total Subjects | 31 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2017-10-03 |
Release Version | 1 |
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Collection:
Collection ID: | CO000802 |
Collection Summary: | Serum collected via existing intravenous or arterial catheter |
Collection Protocol Comments: | T0: collected before carnitine or placebo administration, T24: collected 24h after administration of L-carnitine or placebo (±4h), T48: collected 48h after administration of L-carnitine or placebo (±4h) |
Sample Type: | Blood serum |
Collection Method: | via existing intravenous or arterial catheter |
Collection Frequency: | 1/timepoint, 3 collections/48h |
Collection Time: | T0: before administration, T24: 24h after administration (±4h), T48: 48h after administration (±4h) |
Volumeoramount Collected: | 10mL |
Storage Conditions: | Initial RT then -80°C following processing (within 2h of collection) |
Collection Vials: | SST: Becton-Dickinson 10mL vacutainer Serum Separator tubes |
Storage Vials: | Sterile 1mL cryovials |
Collection Tube Temp: | RT |
Additives: | None |
Blood Serum Or Plasma: | Serum |