Summary of Study ST000785
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000571. The data can be accessed directly via it's Project DOI: 10.21228/M8VM2M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000785 |
Study Title | Pharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock |
Study Type | multiple timepoints; patients with severe sepsis or septic shock |
Study Summary | phase I study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
Institute | University of Michigan |
Department | Clinical Pharmacy |
Laboratory | The NMR Metabolomics Laboratory (Stringer) |
Last Name | Stringer |
First Name | Kathleen |
Address | University Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105 |
NMRmetabolomics@umich.edu | |
Phone | none |
Submit Date | 2016-12-08 |
Num Groups | 2 |
Total Subjects | 31 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2017-10-03 |
Release Version | 1 |
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Treatment:
Treatment ID: | TR000822 |
Treatment Summary: | Intravenous carnitine |
Treatment Protocol Comments: | Non-treatment group: equivalent volume of saline placebo |
Treatment Compound: | L-carnitine |
Treatment Route: | 4g bolus followed by an 8g infusion over 12h |
Treatment Dose: | 12g |
Treatment Doseduration: | 12h (following initial 4g bolus) |