Summary of Study ST000785
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000571. The data can be accessed directly via it's Project DOI: 10.21228/M8VM2M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000785 |
Study Title | Pharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock |
Study Type | multiple timepoints; patients with severe sepsis or septic shock |
Study Summary | phase I study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
Institute | University of Michigan |
Department | Clinical Pharmacy |
Laboratory | The NMR Metabolomics Laboratory (Stringer) |
Last Name | Stringer |
First Name | Kathleen |
Address | University Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105 |
NMRmetabolomics@umich.edu | |
Phone | none |
Submit Date | 2016-12-08 |
Num Groups | 2 |
Total Subjects | 31 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2017-10-03 |
Release Version | 1 |
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Subject:
Subject ID: | SU000808 |
Subject Type: | Human |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |
Age Or Age Range: | 39-93 years |
Weight Or Weight Range: | 55-130 KG |
Gender: | males and females |
Human Race: | Caucasian (C) and African American (AA) |
Human Inclusion Criteria: | Suspicion of or confirmed infection; two or more systemic infmammatory response syndrome criteria; hypotension requiring vasopressors despite volume resuscitation; a cumulative vasopressor index of 3 or more after 4 hours of administration; and a SOFA score of at least 5. |
Human Exclusion Criteria: | Age less than 18; greater than 16h after septic shock recognition; a Do Not Resuscitate order; or known inborn error of metaboloism. |
Species Group: | Human |