Summary of Study ST001872

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001181. The data can be accessed directly via it's Project DOI: 10.21228/M82418 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001872
Study TitleUntargeted LC-MS metabolomics analysis of cecal content of mice treated with TCDD vs. vehicle control (part II)
Study TypeUntargeted metabolomics
Study SummarySix-week-old female wildtype (WT) C57BL/6 mice were administered a single 100µl intraperitoneal injection containing sterile corn oil (VEH group) or an intraperitoneal injection of 10µg/kg TCDD suspended within sterile corn oil (TCDD group). At the 72h time point following TCDD or VEH exposure, the mice were humanely euthanized by an overdose of inhaled isoflurane. During necropsy, cecal content and blood serum samples were collected for untargeted metabolomics profiling.
Institute
University of South Carolina School of Medicine
DepartmentDepartment of Pathology
Laboratory(On behalf of) Mitzi Nagarkatti Lab
Last NameLai
First NameYunjia
Address135 Dauer Drive, Chapel Hill, NC 27599
Emailyunjia.lai@outlook.com
Phone919-480-5489
Submit Date2021-07-18
Num Groups2
Total Subjects20
Num Females20
PublicationsChemosphere
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2021-08-30
Release Version1
Yunjia Lai Yunjia Lai
https://dx.doi.org/10.21228/M82418
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN003034
Analysis type MS
Chromatography type Reversed phase
Chromatography system Thermo Vanquish
Column Waters Acquity BEH HSS T3 (100 x 2.1mm,1.8um)
MS Type ESI
MS instrument type Orbitrap
MS instrument name Thermo Q Exactive Orbitrap
Ion Mode POSITIVE
Units m/z
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