Summary of Study ST002942
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001830. The data can be accessed directly via it's Project DOI: 10.21228/M85H91 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST002942 |
Study Title | Targeted analysis of short chain fatty acids for the XMaS clinical trial. |
Study Summary | The Xanthohumol microbiome and signature (XMaS) study in healthy adults was a phase I, triple-masked, placebo-controlled clinical trial in healthy adults investigating effects of a natural product supplement of gut microbiome composition and metabolism. Xanthohumol, a flavonoid from the hops plant or placebo was administered to 27 healthy adults daily for eight weeks. Fecal, plasma, and 24-hr urine collections were obtained from participants at baseline and 2-week intervals. The main objective of this study was to quantify short chain fatty acids from fecal samples of particiapnts in the XMaS trail |
Institute | Oregon State University |
Last Name | Jamieson |
First Name | Paige |
Address | 307 LINUS PAULING SCIENCE CTR |
jamiesop@oregonstate.edu | |
Phone | 5417379804 |
Submit Date | 2023-10-22 |
Analysis Type Detail | LC-MS |
Release Date | 2024-01-01 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN004827 |
---|---|
Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | Waters Acquity I-Class |
Column | Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um) |
MS Type | ESI |
MS instrument type | Triple quadrupole |
MS instrument name | Waters Xevo TQ-XS |
Ion Mode | NEGATIVE |
Units | mg/g |
Chromatography:
Chromatography ID: | CH003647 |
Instrument Name: | Waters Acquity I-Class |
Column Name: | Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um) |
Column Temperature: | 40 |
Flow Gradient: | from 0 to 2 min, 15% B; from 2 to 11 min 15-55% B; from 11 to 12 min, 100% B; from 12 to 12.5 min, 100-15% B; and from 12.5 to 15 min, 15% B |
Flow Rate: | 0.35 mL/min |
Solvent A: | water with 0.01% formic acid |
Solvent B: | acetonitrile with 0.01% formic acid |
Chromatography Type: | Reversed phase |