Summary of Study ST002942
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001830. The data can be accessed directly via it's Project DOI: 10.21228/M85H91 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST002942 |
| Study Title | Targeted analysis of short chain fatty acids for the XMaS clinical trial. |
| Study Summary | The Xanthohumol microbiome and signature (XMaS) study in healthy adults was a phase I, triple-masked, placebo-controlled clinical trial in healthy adults investigating effects of a natural product supplement of gut microbiome composition and metabolism. Xanthohumol, a flavonoid from the hops plant or placebo was administered to 27 healthy adults daily for eight weeks. Fecal, plasma, and 24-hr urine collections were obtained from participants at baseline and 2-week intervals. The main objective of this study was to quantify short chain fatty acids from fecal samples of particiapnts in the XMaS trail |
| Institute | Oregon State University |
| Last Name | Jamieson |
| First Name | Paige |
| Address | 307 LINUS PAULING SCIENCE CTR |
| jamiesop@oregonstate.edu | |
| Phone | 5417379804 |
| Submit Date | 2023-10-22 |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-01-01 |
| Release Version | 1 |
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Combined analysis:
| Analysis ID | AN004827 |
|---|---|
| Analysis type | MS |
| Chromatography type | Reversed phase |
| Chromatography system | Waters Acquity I-Class |
| Column | Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um) |
| MS Type | ESI |
| MS instrument type | Triple quadrupole |
| MS instrument name | Waters Xevo TQ-XS |
| Ion Mode | NEGATIVE |
| Units | mg/g |
MS:
| MS ID: | MS004573 |
| Analysis ID: | AN004827 |
| Instrument Name: | Waters Xevo TQ-XS |
| Instrument Type: | Triple quadrupole |
| MS Type: | ESI |
| MS Comments: | Metabolites (acetate, propionate, butyrate, lactate, valerate) were verified by matching m/z value, retention times, and product ions of SRM transitions with those of authenticated standards. TargetLynx Application Manager was used for data processing. |
| Ion Mode: | NEGATIVE |
