Summary of Study ST003072

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001914. The data can be accessed directly via it's Project DOI: 10.21228/M89T5V This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003072
Study TitleInvestigation of polar metabolites by targeted LC-MS analysis from mouse adult or embryonic CSF and from adult serum.
Study SummaryTo maximize discovery from samples with limited amounts, we optimized a method to detect the thyroid hormones ( 3,5,3’-L-triiodothyronine (T3) and 3,5,3’5’-L-tetraiodothyronine (T4)) as well as polar metabolites from central carbon metabolism from mouse adult or embryonic CSF and from adult mouse serum. Samples were ran on reverse phase and HILIC chromatography respectively. For polar metabolite analysis, we employed targeted metabolomics profiling of a panel of 200 compounds. We interrogated relative changes between fresh and frozen adult (male or female) CSF compared to fresh and frozen embryonic CSF. This data presents results from polar HILIC chromatography
Institute
Boston Childrens Hospital
DepartmentPathology
LaboratoryKanarek Lab
Last NamePetrova
First NameBoryana
Address300 Longwood Av
Emailboryana.petrova@childrens.harvard.edu
Phone617
Submit Date2024-01-10
Num Groups7
Total Subjects19
Num Males8
Num Females6
Study Commentsembryos also investigated. samples split for fresh and frozen conditions
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2024-02-14
Release Version1
Boryana Petrova Boryana Petrova
https://dx.doi.org/10.21228/M89T5V
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Sample type Storage condition Sex
SA332248RF402Adult CSF Fresh Female
SA332249RF403Adult CSF Fresh Female
SA332250RF401Adult CSF Fresh Female
SA332251RF400Adult CSF Fresh Female
SA332252RF399Adult CSF Fresh Male
SA332253RF398Adult CSF Fresh Male
SA332254RF397Adult CSF Fresh Male
SA332255RF396Adult CSF Fresh Male
SA332256RF390Adult CSF Frozen Female
SA332257RF389Adult CSF Frozen Female
SA332258RF387Adult CSF Frozen Female
SA332259RF388Adult CSF Frozen Female
SA332260RF383Adult CSF Frozen Male
SA332261RF385Adult CSF Frozen Male
SA332262RF384Adult CSF Frozen Male
SA332263RF386Adult CSF Frozen Male
SA332264RF408Embryonic CSF Fresh Embryo
SA332265RF407Embryonic CSF Fresh Embryo
SA332266RF405Embryonic CSF Fresh Embryo
SA332267RF404Embryonic CSF Fresh Embryo
SA332268RF406Embryonic CSF Fresh Embryo
SA332269RF395Embryonic CSF Frozen Embryo
SA332270RF391Embryonic CSF Frozen Embryo
SA332271RF392Embryonic CSF Frozen Embryo
SA332272RF393Embryonic CSF Frozen Embryo
SA332273RF394Embryonic CSF Frozen Embryo
SA332274RF382Mock Fresh Embryo
SA332275RF381Mock Fresh Female
SA332276RF380Mock Fresh Male
SA332277RF379Mock Frozen Embryo
SA332278RF378Mock Frozen Female
SA332279RF377Mock Frozen Male
SA332280RF411Serum Fresh Male
SA332281RF412Serum Fresh Male
SA332282RF409Serum Frozen Male
SA332283RF410Serum Frozen Male
Showing results 1 to 36 of 36
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