Summary of Study ST001959

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001246. The data can be accessed directly via it's Project DOI: 10.21228/M8NM5W This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001959
Study TitleInvestigation of serum metabolites in the AMPK intestinal KO mice
Study SummaryConducted serum untargeted metabolomics analysis in AMP-activated protein kinase (AMPK) intestinal KO mice and control mice under high-fat diet (HFD) conditions
City of Hope National Medical Center
DepartmentDiabetes Complications & Metabolism
Last NameZhang
First NameEryun
Address1500 Duarte Rd, Duarte, CA91010
Submit Date2021-10-27
Raw Data AvailableYes
Raw Data File Type(s)mzXML
Analysis Type DetailLC-MS
Release Date2022-01-08
Release Version1
Eryun Zhang Eryun Zhang application/zip

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Combined analysis:

Analysis ID AN003194
Analysis type MS
Chromatography type HILIC
Chromatography system Agilent 1290 Infinity
Column Waters Acquity BEH Amide (150 x 2.1mm, 1.7um)
MS instrument type QTOF
MS instrument name ABI Sciex 5600 TripleTOF
Units Peak area


MS ID:MS002972
Analysis ID:AN003194
Instrument Name:ABI Sciex 5600 TripleTOF
Instrument Type:QTOF
MS Comments:UHPLC-MS raw data files were converted into mzXML format using the “msconvert” program from Pro-teoWizard and then analyzed by the XCMS 67 and CAMERA toolbox 68 with R statistical software. The CentWave algorithm in XCMS was used for peak detection. The parameter “peak-width” was set as (5, 20) in units of seconds, referring to the minimum and maximum peak widths for peak detection. The pa-rameter ‘‘snthresh’’ is set as 3 for sensitive peak detection. For multiple UHPLC–MS data files, an or-dered bijective interpolated warping (OBI-Warp) algorithm in XCMS was used for peak alignment.