Summary of Study ST002960
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001842. The data can be accessed directly via it's Project DOI: 10.21228/M8MH8P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002960 |
Study Title | Analysis of Lipids Secreted from Fibroblast Young Cells |
Study Summary | In this experimental study, we aimed to understand the potential factors within the secretions of young cells that could trigger the reverse aging of Mid-old cells. To investigate this phenomenon, we co-cultured young cells with Mid-old cells and observed a fascinating outcome: the Mid-old cells exhibited reverse aging and transformed into a more youthful state. To uncover the specific factors responsible for this reverse aging effect, we conducted a detailed analysis of the secreted factors from the young cells. Our analysis focused on a range of biomolecules, including lipids. However, despite our efforts, we did not identify any distinct factors that could be directly attributed to this remarkable reverse aging process. |
Institute | Ajou University Medical Center |
Last Name | Kim |
First Name | Young Hwa |
Address | 206, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, Republic of Korea |
skyblue32@nate.com | |
Phone | +82-10-5153-3636 |
Submit Date | 2023-11-01 |
Raw Data Available | Yes |
Raw Data File Type(s) | mzML |
Analysis Type Detail | LC-MS |
Release Date | 2023-11-22 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN004861 |
---|---|
Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | Agilent 1290 Infinity UHPLC |
Column | Thermo Hypersil GOLD C18 (100 x 2.1mm,1.9um) |
MS Type | ESI |
MS instrument type | Orbitrap |
MS instrument name | Q Exactive™ Hybrid Quadrupole-Orbitrap MS |
Ion Mode | POSITIVE |
Units | Peak area |
MS:
MS ID: | MS004605 |
Analysis ID: | AN004861 |
Instrument Name: | Q Exactive™ Hybrid Quadrupole-Orbitrap MS |
Instrument Type: | Orbitrap |
MS Type: | ESI |
MS Comments: | Obtained UHPLC-Orbitrap-MS/MS RAW files were processed using Lipid Search 4.2TM (Thermo Fisher Scientific, Waltham, MA, USA). Lipid profiling under the following conditions: parent search; 0.2 Da, product search; 5.0 ppm, precursor ion mass tolerance; 8.0 ppm, M-score threshold; 2.0. |
Ion Mode: | POSITIVE |
Analysis Protocol File: | MS_Analysis_lipid.pdf |