Summary of Study ST002970
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001849. The data can be accessed directly via it's Project DOI: 10.21228/M8QB0V This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002970 |
| Study Title | Untargeted metabolomics of fatty alcohol production at time 90 min of bioconversion |
| Study Summary | We demonstrated applications of this system using three different engineered Escherichia coli requiring different cofactors (fatty alcohol, bioluminescence light, and alkane biosynthesis). The results showed that the XR/lactose system could enhance the production of each system by ~2-4-fold. Untargeted metabolomics and transcriptomics analyses revealed that XR only enhanced pathways related to specific cofactor utilization. |
| Institute | Vidyasirimedhi Institute of Science and Technology |
| Last Name | Sutthaphirom |
| First Name | Chalermroj |
| Address | 555, Moo 1, Payubnai, Wangchan, Rayong, 21210, Thailand |
| chalermroj.s_s19@vistec.ac.th | |
| Phone | (+66)063-9639915 |
| Submit Date | 2023-11-06 |
| Num Groups | 2 |
| Total Subjects | 8 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-11-20 |
| Release Version | 1 |
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Project:
| Project ID: | PR001849 |
| Project DOI: | doi: 10.21228/M8QB0V |
| Project Title: | A versatile in situ cofactor enhancing system for meeting cellular demands for engineered metabolic pathways |
| Project Summary: | Incorporation of XR/lactose in engineered microbes could enhance the productivity due to enhancing the sugar utilization and cofactors synthesis. Untargeted metabolomics analysis could provide the pathway involving this profound effect in engineered microbes. This study is Part 1/3 of XR/lactose system demonstrated in E. coli for fatty alcohol production |
| Institute: | Vidyasirimedhi Institute of Science and Technology |
| Last Name: | Sutthaphirom |
| First Name: | Chalermroj |
| Address: | 555, Moo 1, Payubnai, Wangchan, Rayong, 21210, Thailand |
| Email: | chalermroj.s_s19@vistec.ac.th |
| Phone: | (+66)063-9639915 |
