Summary of Study ST001985
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001261. The data can be accessed directly via it's Project DOI: 10.21228/M8QD8K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001985 |
| Study Title | Profiling Plasmodium falciparum parasites and human red blood cells after treatment with MMV693183 |
| Study Summary | Compound MMV693183 was added to either Plasmodium falciparum or uninfected red blood cells. The concentrations used were 240 nM, 24 nM, and 2.4 nM. Untreated parasites and red blood cells were also used as controls. |
| Institute | Pennsylvania State University |
| Last Name | Llinás |
| First Name | Manuel |
| Address | W126 Millennium Science Complex, University Park, PENNSYLVANIA, 16802, USA |
| manuel@psu.edu | |
| Phone | 8148673527 |
| Submit Date | 2021-10-26 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-02-16 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Sample Preparation:
| Sampleprep ID: | SP002072 |
| Sampleprep Summary: | Once samples were obtained, metabolism was quenched with 90% methanol containing 0.25 uM labeled aspartate, cells were centrifuged, and the supernatant was removed by nitrogen drying. Sample was reconstituted in 3% HPLC-grade methanol and run on the instrument. |
| Processing Method: | Wash, spin, quench, spin, dry, store at -80 C until run on the instrument, resuspend |
| Processing Storage Conditions: | On ice |
| Extraction Method: | 90% methanol extraction |
| Extract Cleanup: | Centrifugation and nitrogen drying |
| Sample Resuspension: | 100 uL 3% methanol with 1 uM chlorpropamide |
| Sample Spiking: | 0.25 uM Labelled Aspartate, 1 uM chlorpropamide |
