Summary of study ST000102

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000094. The data can be accessed directly via it's Project DOI: 10.21228/M8X309 This work is supported by NIH grant, U2C- DK119886.


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Study IDST000102
Study TitleCold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster
Study TypeTime course during cold exposure for four genetic lines of flies
Study SummaryMetabolites of cold hardy versus cold susceptible flies were compared using N less than R-based metabolomics. We used 8 replicates per line (2 hardy lines, two susceptible lines), and sampled each line at three time points (before, during and after cold), giving rise to 96 samples total.
University of Florida
DepartmentEntomology and Nematology
Last NameWilliams
First NameCaroline
Submit Date2014-09-26
Num Groups4
Total Subjects96
Raw Data AvailableYes
Raw Data File Type(s).txt,out, .xml, .par, pdata directory has binary files
Uploaded File Size151 M
Analysis Type DetailNMR
Release Date2015-02-03
Release Version1
Caroline Williams Caroline Williams application/zip

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Project ID:PR000094
Project DOI:doi: 10.21228/M8X309
Project Title:Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster
Project Type:Genetic study
Project Summary:Flies that had been selected for fast and slow recovery from a cold-coma (2 replicates of each type) were sampled before, during (at the end of a 3h cold exposure at 0 degC), and after 5 min recovery from cold exposure. We tested the hypothesis that cold adaptation remodelled metabolic networks to make them more robust to the effects of cold.
Institute:University of Florida
Department:Entomology and Nematology
Laboratory:Daniel A. Hahn
Last Name:Hahn
First Name:Daniel
Funding Source:NSF IOS-1051890