Summary of study ST001268

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000853. The data can be accessed directly via it's Project DOI: 10.21228/M8F108 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001268
Study TitleMetabolome data to annotate metabolite origins
Study SummaryPlasma metabolomics from HIV subjects and controls was incorporated with microbiome data to develop Annotation of Metabolite Origins via Networks (AMON).
University of Colorado, Denver
DepartmentAnschutz Medical Campus
Last NameReisdorph
First NameNichole
Address12850 East Montview Blvd, Aurora, CO, 80045, USA
Submit Date2019-10-22
Total Subjects63
Raw Data AvailableYes
Raw Data File Type(s).d
Analysis Type DetailLC-MS
Release Date2019-10-11
Release Version1
Nichole Reisdorph Nichole Reisdorph application/zip

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Project ID:PR000853
Project DOI:doi: 10.21228/M8F108
Project Title:Integrating microbiome and metabolome data to annotate metabolite origins
Project Summary:Untargeted metabolomics of host-associated samples has yielded insights into mechanisms by which microbes modulate health. However, data interpretation is challenged by the complexity of origins of the small molecules measured, which can come from the host, microbes that live within the host, or from other exposures such as diet or the environment. We address this challenge through development of AMON: Annotation of Metabolite Origins via Networks. AMON is an open-source bioinformatics application that can be used to annotate which compounds in the metabolome could have been produced by bacteria present or the host, to evaluate pathway enrichment of host verses microbial metabolites, and to visualize which compounds may have been produced by host versus microbial enzymes in KEGG pathway maps.
Institute:University of Colorado, Denver
Department:Anschutz Medical Campus
Last Name:Reisdorph
First Name:Nichole
Address:12850 East Montview Blvd, Aurora, CO, 80045, USA
Funding Source:NIH