MGP Database

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MGP000018

Ontology/Pathway Information

Entrez Gene ID33
Gene Nameacyl-CoA dehydrogenase, long chain
Gene Symbol ACADL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0031966 IEA:EnsemblCmitochondrial membrane
GO:0005739 IDA:HPACmitochondrion
GO:0003995 TAS:ReactomeFacyl-CoA dehydrogenase activity
GO:0000062 IEA:EnsemblFfatty-acyl-CoA binding
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0004466 ISS:BHF-UCLFlong-chain-acyl-CoA dehydrogenase activity
GO:0016401 ISS:BHF-UCLFpalmitoyl-CoA oxidase activity
GO:0042413 ISS:BHF-UCLPcarnitine catabolic process
GO:0019254 ISS:BHF-UCLPcarnitine metabolic process, CoA-linked
GO:0044242 ISS:BHF-UCLPcellular lipid catabolic process
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0006635 TAS:ReactomePfatty acid beta-oxidation
GO:0033539 ISS:BHF-UCLPfatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042758 IEA:EnsemblPlong-chain fatty acid catabolic process
GO:0045717 ISS:BHF-UCLPnegative regulation of fatty acid biosynthetic process
GO:0046322 ISS:BHF-UCLPnegative regulation of fatty acid oxidation
GO:0055114 ISS:BHF-UCLPoxidation-reduction process
GO:0051289 IEA:EnsemblPprotein homotetramerization
GO:0090181 ISS:BHF-UCLPregulation of cholesterol metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0001659 ISS:BHF-UCLPtemperature homeostasis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_735Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
REACT_2108Beta oxidation of myristoyl-CoA to lauroyl-CoA
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_1473Mitochondrial Fatty Acid Beta-Oxidation
REACT_1541mitochondrial fatty acid beta-oxidation of saturated fatty acids
SMP Pathway Links
SMP IDDescription
SMP00538Carnitine palmitoyl transferase deficiency (I)
SMP00541Carnitine palmitoyl transferase deficiency (II)
SMP00181Ethylmalonic Encephalopathy
SMP00051Fatty acid Metabolism
SMP00185Glutaric Aciduria Type I
SMP00539Long chain acyl-CoA dehydrogenase deficiency (LCAD)
SMP00542Medium chain acyl-coa dehydrogenase deficiency (MCAD)
SMP00482Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
SMP00480Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
SMP00568Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (SCHAD)
SMP00235Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)
SMP00545Trifunctional protein deficiency
SMP00540Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)
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