MGP Database

MGP000027

Ontology/Pathway Information

Entrez Gene ID43
Gene Nameacetylcholinesterase (Yt blood group)
Gene Symbol ACHE
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031225 IEA:UniProtKB-KWCanchored component of membrane
GO:0005605 NAS:HGNCCbasal lamina
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0009986 IEA:EnsemblCcell surface
GO:0005576 TAS:UniProtKBCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0005794 IDA:HGNCCGolgi apparatus
GO:0016020 IDA:HGNCCmembrane
GO:0031594 IBA:GO_CentralCneuromuscular junction
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0048471 IDA:HGNCCperinuclear region of cytoplasm
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045202 IDA:HGNCCsynapse
GO:0042166 NAS:UniProtKBFacetylcholine binding
GO:0003990 IMP:UniProtKBFacetylcholinesterase activity
GO:0001540 TAS:UniProtKBFbeta-amyloid binding
GO:0004104 IDA:HGNCFcholinesterase activity
GO:0005518 IDA:HGNCFcollagen binding
GO:0016787 IDA:HGNCFhydrolase activity
GO:0043236 IDA:BHF-UCLFlaminin binding
GO:0042803 NAS:UniProtKBFprotein homodimerization activity
GO:0017171 IDA:HGNCFserine hydrolase activity
GO:0006581 IDA:HGNCPacetylcholine catabolic process
GO:0001507 NAS:UniProtKBPacetylcholine catabolic process in synaptic cleft
GO:0042982 TAS:UniProtKBPamyloid precursor protein metabolic process
GO:0007155 TAS:UniProtKBPcell adhesion
GO:0008283 TAS:UniProtKBPcell proliferation
GO:0006260 TAS:UniProtKBPDNA replication
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0007517 TAS:UniProtKBPmuscle organ development
GO:0032223 IC:HGNCPnegative regulation of synaptic transmission, cholinergic
GO:0007399 TAS:UniProtKBPnervous system development
GO:0042136 TAS:ReactomePneurotransmitter biosynthetic process
GO:0045212 IEA:EnsemblPneurotransmitter receptor biosynthetic process
GO:0002076 IEP:HGNCPosteoblast development
GO:0006656 TAS:ReactomePphosphatidylcholine biosynthetic process
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0050714 TAS:UniProtKBPpositive regulation of protein secretion
GO:0051262 IEA:EnsemblPprotein tetramerization
GO:0031623 IEA:EnsemblPreceptor internalization
GO:0001919 IEA:EnsemblPregulation of receptor recycling
GO:0009611 TAS:UniProtKBPresponse to wounding
GO:0060041 IEA:EnsemblPretina development in camera-type eye
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007416 TAS:UniProtKBPsynapse assembly
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121401Glycerophospholipid biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_13685Neuronal System
REACT_13583Neurotransmitter Clearance In The Synaptic Cleft
REACT_160078Peptide hormone metabolism
REACT_120870Phospholipid metabolism
REACT_121238Synthesis of PC
REACT_19189Synthesis, secretion, and deacylation of Ghrelin
REACT_13477Transmission across Chemical Synapses
SMP Pathway Links
SMP IDDescription
SMP00025Phospholipid Biosynthesis
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