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MGP000068

Record overview

MGPD IDMGP000068
Gene ID126
SpeciesHomo sapiens (Human)
Gene Namealcohol dehydrogenase 1C (class I), gamma polypeptide
Gene Symbol ADH1C
SynonymsADH3;
Alternate namesalcohol dehydrogenase 1C; ADH, gamma subunit; alcohol dehydrogenase 3 (class I), gamma polypeptide; aldehyde reductase;
Chromosome4
Map Location4q23
EC Number1.1.1.1
SummaryThis gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ADH1C

Proteins

alcohol dehydrogenase 1C
Refseq ID:NP_000660
Protein GI:4501933
UniProt ID:P00326
mRNA ID:NM_000669
Length:375
RefSeq Status:
MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGK
CRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFG
LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ
NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTF
 
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