MGP Database

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MGP000071

Ontology/Pathway Information

Entrez Gene ID131
Gene Namealcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Gene Symbol ADH7
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005576 IDA:GOCCextracellular region
GO:0004024 IDA:UniProtKBFalcohol dehydrogenase activity, zinc-dependent
GO:0004022 TAS:UniProtKBFalcohol dehydrogenase (NAD) activity
GO:0004031 IDA:UniProtKBFaldehyde oxidase activity
GO:0035276 IDA:UniProtKBFethanol binding
GO:0048019 IDA:UniProtKBFreceptor antagonist activity
GO:0019841 IDA:UniProtKBFretinol binding
GO:0004745 IDA:UniProtKBFretinol dehydrogenase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0006068 IEA:EnsemblPethanol catabolic process
GO:0006069 IDA:UniProtKBPethanol oxidation
GO:1900116 IDA:GOCPextracellular negative regulation of signal transduction
GO:0010430 IDA:UniProtKBPfatty acid omega-oxidation
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0009617 IDA:UniProtKBPresponse to bacterium
GO:0045471 IDA:UniProtKBPresponse to ethanol
GO:0042573 IEA:EnsemblPretinoic acid metabolic process
GO:0001523 IDA:UniProtKBPretinoid metabolic process
GO:0042572 IEA:EnsemblPretinol metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268767Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
REACT_268601Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)
REACT_268761Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)
REACT_268217Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
REACT_268478Defective CYP19A1 causes Aromatase excess syndrome (AEXS)
REACT_268087Defective CYP1B1 causes Glaucoma
REACT_267893Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)
REACT_268803Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)
REACT_268108Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)
REACT_267734Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)
REACT_268413Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)
REACT_268633Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
REACT_268491Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)
REACT_268326Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)
REACT_268441Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
REACT_267709Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)
REACT_268486Defective FMO3 causes Trimethylaminuria (TMAU)
REACT_267863Defective MAOA causes Brunner syndrome (BRUNS)
REACT_268528Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)
REACT_116125Disease
REACT_34Ethanol oxidation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_13705Phase 1 - Functionalization of compounds
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