MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000075

Ontology/Pathway Information

Entrez Gene ID135
Gene Nameadenosine A2a receptor
Gene Symbol ADORA2A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005887 IMP:UniProtKBCintegral component of plasma membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0001609 IDA:UniProtKBFG-protein coupled adenosine receptor activity
GO:0042802 IPI:IntActFidentical protein binding
GO:0007190 TAS:ReactomePactivation of adenylate cyclase activity
GO:0007188 TAS:ProtIncPadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0006915 TAS:ProtIncPapoptotic process
GO:0008015 TAS:ProtIncPblood circulation
GO:0007596 TAS:ProtIncPblood coagulation
GO:0006171 TAS:ProtIncPcAMP biosynthetic process
GO:0007267 TAS:ProtIncPcell-cell signaling
GO:0006968 TAS:ProtIncPcellular defense response
GO:0007417 TAS:ProtIncPcentral nervous system development
GO:0006954 TAS:ProtIncPinflammatory response
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0006909 TAS:ProtIncPphagocytosis
GO:0010579 IDA:UniProtKBPpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0007600 TAS:ProtIncPsensory perception
GO:0007169 TAS:ReactomePtransmembrane receptor protein tyrosine kinase signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11064Activation of TRKA receptors
REACT_18288Adenosine P1 receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19327G alpha (s) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_11046NGF-independant TRKA activation
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_18342Nucleotide-like (purinergic) receptors
REACT_14797Signaling by GPCR
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00320Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
  logo