MGP Database

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MGP000116

UniProt Annotations

Entry Information
Gene Namealdehyde dehydrogenase 1 family, member A1
Protein EntryAL1A1_HUMAN
UniProt IDP00352
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityRetinal + NAD(+) + H(2)O = retinoate + NADH.
FunctionBinds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). {ECO:0000250}.
PathwayCofactor metabolism; retinol metabolism.
SimilarityBelongs to the aldehyde dehydrogenase family. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomotetramer.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/aldh1a1/";
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