MGP Database

MGP000146

Ontology/Pathway Information

Entrez Gene ID	284
Gene Name	angiopoietin 1
Gene Symbol	ANGPT1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:UniProtKB	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0045121	IDA:UniProtKB	C	membrane raft
GO:0005902	IDA:UniProtKB	C	microvillus
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0030971	IPI:UniProtKB	F	receptor tyrosine kinase binding
GO:0007171	IDA:UniProtKB	P	activation of transmembrane receptor protein tyrosine kinase activity
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0030154	IEA:UniProtKB-KW	P	cell differentiation
GO:0031589	IEA:Ensembl	P	cell-substrate adhesion
GO:0072012	ISS:UniProtKB	P	glomerulus vasculature development
GO:0030097	IEA:Ensembl	P	hemopoiesis
GO:0030210	IDA:UniProtKB	P	heparin biosynthetic process
GO:0001701	IEA:Ensembl	P	in utero embryonic development
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0043066	IDA:UniProtKB	P	negative regulation of apoptotic process
GO:0007162	IDA:UniProtKB	P	negative regulation of cell adhesion
GO:2000352	IDA:UniProtKB	P	negative regulation of endothelial cell apoptotic process
GO:0043524	IEA:Ensembl	P	negative regulation of neuron apoptotic process
GO:0043116	IDA:UniProtKB	P	negative regulation of vascular permeability
GO:0050918	IDA:UniProtKB	P	positive chemotaxis
GO:0043536	IDA:UniProtKB	P	positive regulation of blood vessel endothelial cell migration
GO:0045785	IEA:Ensembl	P	positive regulation of cell adhesion
GO:0010595	IDA:UniProtKB	P	positive regulation of endothelial cell migration
GO:0070374	IDA:UniProtKB	P	positive regulation of ERK1 and ERK2 cascade
GO:0033138	IEA:Ensembl	P	positive regulation of peptidyl-serine phosphorylation
GO:0050731	IDA:UniProtKB	P	positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897	IDA:UniProtKB	P	positive regulation of protein kinase B signaling
GO:0031398	IDA:UniProtKB	P	positive regulation of protein ubiquitination
GO:0002092	IDA:UniProtKB	P	positive regulation of receptor internalization
GO:0034394	IDA:UniProtKB	P	protein localization to cell surface
GO:0014842	IDA:UniProtKB	P	regulation of satellite cell proliferation
GO:0002040	IDA:UniProtKB	P	sprouting angiogenesis
GO:0048014	IDA:UniProtKB	P	Tie signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_12051	Cell surface interactions at the vascular wall
REACT_604	Hemostasis
REACT_12621	Tie2 Signaling