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MGP000154

Record overview

MGPD IDMGP000154
Gene ID293
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
Gene Symbol SLC25A6
Synonyms2; 3; ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y;
Alternate namesADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocator of liver; adenine nucleotide translocator 3; solute carrier family 25 member 6;
ChromosomeX
Map LocationXp22.32 and Yp11.3
SummaryThis gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]
OrthologsView orthologs and multiple alignments for SLC25A6

Proteins

ADP/ATP translocase 3
Refseq ID:NP_001627
Protein GI:156071462
UniProt ID:P12236
mRNA ID:NM_001636
Length:298
RefSeq Status:
MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL
GGVDKHTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKG
MLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI
 
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