MGP Database

MGP000155

Ontology/Pathway Information

Entrez Gene ID	301
Gene Name	annexin A1
Gene Symbol	ANXA1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016323	IEA:UniProtKB-SubCell	C	basolateral plasma membrane
GO:0009986	IDA:BHF-UCL	C	cell surface
GO:0005929	IEA:UniProtKB-SubCell	C	cilium
GO:0001533	IDA:UniProtKB	C	cornified envelope
GO:0005737	TAS:UniProtKB	C	cytoplasm
GO:0005768	IDA:UniProtKB	C	endosome
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:UniProtKB	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0042629	IEA:Ensembl	C	mast cell granule
GO:0031966	IEA:Ensembl	C	mitochondrial membrane
GO:0005634	IDA:BHF-UCL	C	nucleus
GO:0005886	IDA:HPA	C	plasma membrane
GO:0043234	IEA:Ensembl	C	protein complex
GO:0042383	IEA:Ensembl	C	sarcolemma
GO:0031982	IDA:UniProtKB	C	vesicle
GO:0036310	IEA:Ensembl	F	annealing helicase activity
GO:0005544	IDA:UniProtKB	F	calcium-dependent phospholipid binding
GO:0048306	IPI:AgBase	F	calcium-dependent protein binding
GO:0005509	TAS:ProtInc	F	calcium ion binding
GO:0033676	IEA:Ensembl	F	double-stranded DNA-dependent ATPase activity
GO:0004386	IEA:Ensembl	F	helicase activity
GO:0019834	IDA:UniProtKB	F	phospholipase A2 inhibitor activity
GO:0005543	TAS:ProtInc	F	phospholipid binding
GO:0030674	IDA:UniProtKB	F	protein binding, bridging
GO:0005102	TAS:ProtInc	F	receptor binding
GO:0003697	IEA:Ensembl	F	single-stranded DNA binding
GO:0003727	IEA:Ensembl	F	single-stranded RNA binding
GO:0005198	IDA:UniProtKB	F	structural molecule activity
GO:0046632	ISS:BHF-UCL	P	alpha-beta T cell differentiation
GO:0050482	IEA:Ensembl	P	arachidonic acid secretion
GO:0007166	TAS:ProtInc	P	cell surface receptor signaling pathway
GO:0006928	TAS:ProtInc	P	cellular component movement
GO:0071385	IDA:BHF-UCL	P	cellular response to glucocorticoid stimulus
GO:0070301	IEA:Ensembl	P	cellular response to hydrogen peroxide
GO:0032508	IEA:Ensembl	P	DNA duplex unwinding
GO:0036292	IEA:Ensembl	P	DNA rewinding
GO:0031018	IEA:Ensembl	P	endocrine pancreas development
GO:0042063	IEA:Ensembl	P	gliogenesis
GO:0070365	IEA:Ensembl	P	hepatocyte differentiation
GO:0006954	TAS:ProtInc	P	inflammatory response
GO:0030073	IEA:Ensembl	P	insulin secretion
GO:0030216	IDA:UniProtKB	P	keratinocyte differentiation
GO:0043066	TAS:UniProtKB	P	negative regulation of apoptotic process
GO:2000483	IMP:BHF-UCL	P	negative regulation of interleukin-8 secretion
GO:1900138	IEA:Ensembl	P	negative regulation of phospholipase A2 activity
GO:0097350	IMP:BHF-UCL	P	neutrophil clearance
GO:0001780	IMP:BHF-UCL	P	neutrophil homeostasis
GO:0018149	IDA:UniProtKB	P	peptide cross-linking
GO:1900087	IEA:Ensembl	P	positive regulation of G1/S transition of mitotic cell cycle
GO:0033031	IEA:Ensembl	P	positive regulation of neutrophil apoptotic process
GO:0031394	IEA:Ensembl	P	positive regulation of prostaglandin biosynthetic process
GO:0031340	IDA:UniProtKB	P	positive regulation of vesicle fusion
GO:0070459	IEA:Ensembl	P	prolactin secretion
GO:0030850	IEA:Ensembl	P	prostate gland development
GO:0042127	IEA:Ensembl	P	regulation of cell proliferation
GO:0042493	IEA:Ensembl	P	response to drug
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0070555	IEA:Ensembl	P	response to interleukin-1
GO:0043434	IEA:Ensembl	P	response to peptide hormone
GO:0010165	IEA:Ensembl	P	response to X-ray
GO:0007165	TAS:UniProtKB	P	signal transduction

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_14828	Class A/1 (Rhodopsin-like receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_21264	Formyl peptide receptors bind formyl peptides and many other ligands
REACT_19231	G alpha (i) signalling events
REACT_18283	G alpha (q) signalling events
REACT_120966	Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14819	Peptide ligand-binding receptors
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction