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MGP000156

Record overview

MGPD IDMGP000156
Gene ID302
SpeciesHomo sapiens (Human)
Gene Nameannexin A2
Gene Symbol ANXA2
SynonymsP36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; HEL-S-270;
Alternate namesannexin A2; annexin II; annexin-2; calpactin I heavy chain; calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; lipocortin II; placental anticoagulant protein IV; protein I;
Chromosome15
Map Location15q22.2
SummaryThis gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ANXA2

Proteins

annexin A2 isoform 1
Refseq ID:NP_001002858
Protein GI:50845388
UniProt ID:P07355
mRNA ID:NM_001002858
Length:357
RefSeq Status:
MGRQLAGCGDAGKKASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKE
LASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAED
GSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKG
TRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
 
annexin A2 isoform 2
Refseq ID:NP_001129487
Protein GI:209862831
UniProt ID:P07355
mRNA ID:NM_001136015
Length:339
RefSeq Status:
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVIL
GLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYD
AGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM
LKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
 
annexin A2 isoform 2
Refseq ID:NP_001002857
Protein GI:50845386
UniProt ID:P07355
mRNA ID:NM_001002857
Length:339
RefSeq Status:
Protein sequence is identical to GI:209862831 (mRNA isoform)
 
annexin A2 isoform 2
Refseq ID:NP_004030
Protein GI:4757756
UniProt ID:P07355
mRNA ID:NM_004039
Length:339
RefSeq Status:
Protein sequence is identical to GI:209862831 (mRNA isoform)
 
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