MGP Database

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MGP000181

Ontology/Pathway Information

Entrez Gene ID358
Gene Nameaquaporin 1 (Colton blood group)
Gene Symbol AQP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045177 IDA:UniProtKBCapical part of cell
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0043679 IEA:EnsemblCaxon terminus
GO:0009925 IDA:UniProtKBCbasal plasma membrane
GO:0016323 IDA:UniProtKBCbasolateral plasma membrane
GO:0005903 IDA:UniProtKBCbrush border
GO:0031526 IDA:UniProtKBCbrush border membrane
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0031965 IDA:UniProtKBCnuclear membrane
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0042383 IDA:UniProtKBCsarcolemma
GO:0020003 ISS:UniProtKBCsymbiont-containing vacuole
GO:0008519 IDA:UniProtKBFammonium transmembrane transporter activity
GO:0035379 IDA:UniProtKBFcarbon dioxide transmembrane transporter activity
GO:0015168 IDA:UniProtKBFglycerol transmembrane transporter activity
GO:0005223 IDA:UniProtKBFintracellular cGMP activated cation channel activity
GO:0030184 IDA:UniProtKBFnitric oxide transmembrane transporter activity
GO:0005267 IMP:UniProtKBFpotassium channel activity
GO:0015079 ISS:UniProtKBFpotassium ion transmembrane transporter activity
GO:0022857 IDA:UniProtKBFtransmembrane transporter activity
GO:0015250 IDA:UniProtKBFwater channel activity
GO:0005372 IDA:UniProtKBFwater transmembrane transporter activity
GO:0072488 IDA:GOCPammonium transmembrane transport
GO:0015696 IDA:UniProtKBPammonium transport
GO:0015701 TAS:ReactomePbicarbonate transport
GO:0048593 IEA:EnsemblPcamera-type eye morphogenesis
GO:0035378 IDA:UniProtKBPcarbon dioxide transmembrane transport
GO:0015670 IDA:UniProtKBPcarbon dioxide transport
GO:0098655 IDA:GOCPcation transmembrane transport
GO:0019725 IDA:UniProtKBPcellular homeostasis
GO:0071474 IMP:UniProtKBPcellular hyperosmotic response
GO:0071320 IDA:UniProtKBPcellular response to cAMP
GO:0071280 IDA:UniProtKBPcellular response to copper ion
GO:0071549 IDA:UniProtKBPcellular response to dexamethasone stimulus
GO:0070301 IDA:UniProtKBPcellular response to hydrogen peroxide
GO:0071456 IDA:UniProtKBPcellular response to hypoxia
GO:0071241 IDA:UniProtKBPcellular response to inorganic substance
GO:0071260 IDA:UniProtKBPcellular response to mechanical stimulus
GO:0071288 IDA:UniProtKBPcellular response to mercury ion
GO:0071732 IDA:UniProtKBPcellular response to nitric oxide
GO:0071300 IDA:UniProtKBPcellular response to retinoic acid
GO:0071472 IDA:UniProtKBPcellular response to salt stress
GO:0033554 IDA:UniProtKBPcellular response to stress
GO:0034644 IDA:UniProtKBPcellular response to UV
GO:0006884 IMP:UniProtKBPcell volume homeostasis
GO:0033326 IEP:UniProtKBPcerebrospinal fluid secretion
GO:0006182 IDA:UniProtKBPcGMP biosynthetic process
GO:0051458 IEA:EnsemblPcorticotropin secretion
GO:0030950 IMP:UniProtKBPestablishment or maintenance of actin cytoskeleton polarity
GO:0003094 IEA:EnsemblPglomerular filtration
GO:0015793 IDA:UniProtKBPglycerol transport
GO:0042538 IEA:EnsemblPhyperosmotic salinity response
GO:0021670 IEP:UniProtKBPlateral ventricle development
GO:0044241 IEA:EnsemblPlipid digestion
GO:0085018 IMP:UniProtKBPmaintenance of symbiont-containing vacuole by host
GO:0072220 IEA:EnsemblPmetanephric descending thin limb development
GO:0072239 IEA:EnsemblPmetanephric glomerulus vasculature development
GO:0072232 IEA:EnsemblPmetanephric proximal convoluted tubule segment 2 development
GO:0072230 IEA:EnsemblPmetanephric proximal straight tubule development
GO:0050891 IEP:UniProtKBPmulticellular organismal water homeostasis
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0043154 IMP:UniProtKBPnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0030185 IDA:UniProtKBPnitric oxide transport
GO:0042476 IEP:UniProtKBPodontogenesis
GO:0030157 IEP:UniProtKBPpancreatic juice secretion
GO:0045766 IMP:UniProtKBPpositive regulation of angiogenesis
GO:0010634 IEA:EnsemblPpositive regulation of epithelial cell migration
GO:0048146 IDA:UniProtKBPpositive regulation of fibroblast proliferation
GO:0010592 IEA:EnsemblPpositive regulation of lamellipodium assembly
GO:0046878 IMP:UniProtKBPpositive regulation of saliva secretion
GO:0071805 IMP:GOCPpotassium ion transmembrane transport
GO:0006813 ISS:UniProtKBPpotassium ion transport
GO:0070295 IEA:EnsemblPrenal water absorption
GO:0003097 IDA:UniProtKBPrenal water transport
GO:0042493 IDA:UniProtKBPresponse to drug
GO:0043627 IEA:EnsemblPresponse to estrogen
GO:0033363 IEA:EnsemblPsecretory granule organization
GO:0019233 IEA:EnsemblPsensory perception of pain
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0035377 IDA:UniProtKBPtransepithelial water transport
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006833 IDA:UniProtKBPwater transport
GO:0042060 IEA:EnsemblPwound healing
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23887Aquaporin-mediated transport
REACT_121329Erythrocytes take up carbon dioxide and release oxygen
REACT_121380Erythrocytes take up oxygen and release carbon dioxide
REACT_111217Metabolism
REACT_120969O2/CO2 exchange in erythrocytes
REACT_23826Passive transport by Aquaporins
REACT_15518Transmembrane transport of small molecules
REACT_24023Vasopressin regulates renal water homeostasis via Aquaporins
SMP Pathway Links
SMP IDDescription
SMP00133Amiloride Action Pathway
SMP00090Bendroflumethiazide Action Pathway
SMP00583Blue diaper syndrome
SMP00088Bumetanide Action Pathway
SMP00078Chlorothiazide Action Pathway
SMP00122Chlorthalidone Action Pathway
SMP00103Cyclothiazide Action Pathway
SMP00723Cystinuria
SMP00135Eplerenone Action Pathway
SMP00097Ethacrynic Acid Action Pathway
SMP00115Furosemide Action Pathway
SMP00245Glucose Transporter Defect (SGLT2)
SMP00189Hartnup Disorder
SMP00100Hydrochlorothiazide Action Pathway
SMP00108Hydroflumethiazide Action Pathway
SMP00193Iminoglycinuria
SMP00584Iminoglycinuria
SMP00110Indapamide Action Pathway
SMP00483Kidney Function
SMP00197Lysinuric Protein Intolerance
SMP00585Lysinuric protein intolerance (LPI)
SMP00081Methyclothiazide Action Pathway
SMP00105Metolazone Action Pathway
SMP00080Polythiazide Action Pathway
SMP00091Quinethazone Action Pathway
SMP00184Renal Glucosuria
SMP00134Spironolactone Action Pathway
SMP00118Torsemide Action Pathway
SMP00132Triamterene Action Pathway
SMP00121Trichlormethiazide Action Pathway
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