MGP Database

MGP000195

Ontology/Pathway Information

Entrez Gene ID	383
Gene Name	arginase 1
Gene Symbol	ARG1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	TAS:ProtInc	C	cytoplasm
GO:0005829	TAS:Reactome	C	cytosol
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0043005	IEA:Ensembl	C	neuron projection
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0004053	EXP:Reactome	F	arginase activity
GO:0030145	IEA:Ensembl	F	manganese ion binding
GO:0006527	TAS:ProtInc	P	arginine catabolic process
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0071549	IEA:Ensembl	P	cellular response to dexamethasone stimulus
GO:0071377	IEA:Ensembl	P	cellular response to glucagon stimulus
GO:0070301	IEA:Ensembl	P	cellular response to hydrogen peroxide
GO:0071353	IEA:Ensembl	P	cellular response to interleukin-4
GO:0071222	IEA:Ensembl	P	cellular response to lipopolysaccharide
GO:0071560	IEA:Ensembl	P	cellular response to transforming growth factor beta stimulus
GO:0032964	IEA:Ensembl	P	collagen biosynthetic process
GO:0001889	IEA:Ensembl	P	liver development
GO:0030324	IEA:Ensembl	P	lung development
GO:0060056	IEA:Ensembl	P	mammary gland involution
GO:0060135	IEA:Ensembl	P	maternal process involved in female pregnancy
GO:0001938	IEA:Ensembl	P	positive regulation of endothelial cell proliferation
GO:0070207	IEA:Ensembl	P	protein homotrimerization
GO:0010963	IEA:Ensembl	P	regulation of L-arginine import
GO:0014075	IEA:Ensembl	P	response to amine
GO:0043200	IEA:Ensembl	P	response to amino acid
GO:0048678	IEA:Ensembl	P	response to axon injury
GO:0046686	IEA:Ensembl	P	response to cadmium ion
GO:0042493	IEA:Ensembl	P	response to drug
GO:0009635	IEA:Ensembl	P	response to herbicide
GO:0010042	IEA:Ensembl	P	response to manganese ion
GO:0051597	IEA:Ensembl	P	response to methylmercury
GO:0010269	IEA:Ensembl	P	response to selenium ion
GO:0033189	IEA:Ensembl	P	response to vitamin A
GO:0033197	IEA:Ensembl	P	response to vitamin E
GO:0010043	IEA:Ensembl	P	response to zinc ion
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0000050	TAS:Reactome	P	urea cycle

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives
REACT_847	Urea cycle

SMP Pathway Links

SMP ID	Description
SMP00020	Arginine and Proline Metabolism
SMP00362	Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
SMP00357	Argininemia
SMP00003	Argininosuccinic Aciduria
SMP00002	Carbamoyl Phosphate Synthetase Deficiency
SMP00001	Citrullinemia Type I
SMP00504	Creatine deficiency, guanidinoacetate methyltransferase deficiency
SMP00188	Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
SMP00506	Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]
SMP00505	Hyperornithinemia with gyrate atrophy (HOGA)
SMP00361	Hyperprolinemia Type I
SMP00360	Hyperprolinemia Type II
SMP00507	L-arginine:glycine amidinotransferase deficiency
SMP00363	Ornithine Aminotransferase Deficiency (OAT Deficiency)
SMP00205	Ornithine Transcarbamylase Deficiency (OTC Deficiency)
SMP00207	Prolidase Deficiency (PD)
SMP00208	Prolinemia Type II
SMP00059	Urea Cycle