MGP Database

MGP000225

Ontology/Pathway Information

Entrez Gene ID	440
Gene Name	asparagine synthetase (glutamine-hydrolyzing)
Gene Symbol	ASNS
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	TAS:Reactome	C	cytosol
GO:0004066	IDA:UniProtKB	F	asparagine synthase (glutamine-hydrolyzing) activity
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0048037	IEA:Ensembl	F	cofactor binding
GO:0006987	TAS:Reactome	P	activation of signaling protein activity involved in unfolded protein response
GO:0006529	IC:UniProtKB	P	asparagine biosynthetic process
GO:0008652	TAS:Reactome	P	cellular amino acid biosynthetic process
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0044267	TAS:Reactome	P	cellular protein metabolic process
GO:0042149	IDA:UniProtKB	P	cellular response to glucose starvation
GO:0032870	IEA:Ensembl	P	cellular response to hormone stimulus
GO:0030968	TAS:Reactome	P	endoplasmic reticulum unfolded protein response
GO:0006541	IEA:UniProtKB-KW	P	glutamine metabolic process
GO:0070981	IEA:UniProtKB-UniPathway	P	L-asparagine biosynthetic process
GO:0001889	IEA:Ensembl	P	liver development
GO:0043066	IMP:UniProtKB	P	negative regulation of apoptotic process
GO:0045931	IDA:UniProtKB	P	positive regulation of mitotic cell cycle
GO:0043200	IEA:Ensembl	P	response to amino acid
GO:0032354	IEA:Ensembl	P	response to follicle-stimulating hormone
GO:0009416	IEA:Ensembl	P	response to light stimulus
GO:0009612	IEA:Ensembl	P	response to mechanical stimulus
GO:0031427	IEA:Ensembl	P	response to methotrexate
GO:0009636	IEA:Ensembl	P	response to toxic substance
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_238	Amino acid synthesis and interconversion (transamination)
REACT_18355	ATF4 activates genes
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives
REACT_17015	Metabolism of proteins
REACT_18277	PERK regulates gene expression
REACT_18356	Unfolded Protein Response (UPR)

SMP Pathway Links