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MGP000252

Record overview

MGPD IDMGP000252
Gene ID496
SpeciesHomo sapiens (Human)
Gene NameATPase, H+/K+ exchanging, beta polypeptide
Gene Symbol ATP4B
SynonymsATP6B;
Alternate namespotassium-transporting ATPase subunit beta; proton pump beta chain; gastric H+/K+ ATPase beta subunit; gastric H(+)/K(+) ATPase subunit beta; gastric hydrogen-potassium ATPase, beta; potassium-transporting ATPase beta chain; ATPase, H+/K+ transporting, beta polypeptide;
Chromosome13
Map Location13q34
SummaryThe protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ATP4B

Proteins

potassium-transporting ATPase subunit beta
Refseq ID:NP_000696
Protein GI:4557339
UniProt ID:P51164
mRNA ID:NM_000705
Length:291
RefSeq Status:
MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNV
SDNRTWADLTQTLHAFLAGYSPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRVD
CAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
 
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