MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000252

UniProt Annotations

Entry Information
Gene NameATPase, H+/K+ exchanging, beta polypeptide
Protein EntryATP4B_HUMAN
UniProt IDP51164
SpeciesHuman
Comments
Comment typeDescription
DomainThe C-terminal lobe folds into an immunoglobulin-like domain and mediates cell adhesion properties. {ECO:0000269|PubMed:19694409}.
FunctionRequired for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. {ECO:0000269|PubMed:19694409}.
SimilarityBelongs to the X(+)/potassium ATPases subunit beta family. {ECO:0000305}.
Subcellular LocationCell membrane; Single-pass type II membrane protein.
SubunitComposed of two subunits: alpha (catalytic) and beta.
  logo