MGP Database

MGP000293

Record overview

MGPD ID	MGP000293
Gene ID	587
Species	Homo sapiens (Human)
Gene Name	branched chain amino-acid transaminase 2, mitochondrial
Gene Symbol	BCAT2
Synonyms	BCAM; BCT2; PP18; BCATM;
Alternate names	branched-chain-amino-acid aminotransferase, mitochondrial; branched chain aminotransferase 2, mitochondrial; placental protein 18;
Chromosome	19
Map Location	19q13
EC Number	2.6.1.42
Summary	This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Orthologs	View orthologs and multiple alignments for BCAT2

Proteins

branched-chain-amino-acid aminotransferase, mitochondrial isoform a precursor

Refseq ID:	NP_001181
Protein GI:	50658084
UniProt ID:	O15382
mRNA ID:	NM_001190
Length:	392
RefSeq Status:

`MAAAALGQIWARKLLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQ LFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAY FPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQS LLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV`

transit_peptide: 1..27
calculated_mol_wt: 3042
peptide sequence: 
MAAAALGQIWARKLLSVPWLLCGPRRY

mat_peptide: 28..392
product: branched-chain-amino-acid aminotransferase, mitochondrial isoform a
calculated_mol_wt: 41264
peptide sequence: 
ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRM
LRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGN
YKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL
EEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV

branched-chain-amino-acid aminotransferase, mitochondrial isoform b

Refseq ID:	NP_001158245
Protein GI:	258614015
UniProt ID:	O15382
mRNA ID:	NM_001164773
Length:	300
RefSeq Status:

`MAAAALGQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFV ILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVI LPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV`

transit_peptide: 1..27
calculated_mol_wt: 3042
peptide sequence: 
MAAAALGQIWARKLLSVPWLLCGPRRY

mat_peptide: 28..392
product: branched-chain-amino-acid aminotransferase, mitochondrial isoform a
calculated_mol_wt: 41264
peptide sequence: 
ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRM
LRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGN
YKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL
EEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV

branched-chain-amino-acid aminotransferase, mitochondrial isoform c

Refseq ID:	NP_001271254
Protein GI:	547235678
UniProt ID:	O15382
mRNA ID:	NM_001284325
Length:	352
RefSeq Status:

`MTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFD KLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLV QQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGT ACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV`