MGP Database

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MGP000338

UniProt Annotations

Entry Information
Gene Namebone marrow stromal cell antigen 1
Protein EntryBST1_HUMAN
UniProt IDQ10588
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q10588-1; Sequence=Displayed; Name=2; IsoId=Q10588-2; Sequence=VSP_055507; Note=No experimental confirmation available.;
Catalytic ActivityNAD(+) + H(2)O = ADP-D-ribose + nicotinamide.
FunctionSynthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. {ECO:0000269|PubMed:11866528}.
SimilarityBelongs to the ADP-ribosyl cyclase family. {ECO:0000305}.
Subcellular LocationCell membrane; Lipid-anchor, GPI-anchor.
SubunitHomodimer.
Tissue SpecificityWidely expressed.
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