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MGP000371

Record overview

MGPD IDMGP000371
Gene ID760
SpeciesHomo sapiens (Human)
Gene Namecarbonic anhydrase II
Gene Symbol CA2
SynonymsCAC; CAII; Car2; CA-II; HEL-76;
Alternate namescarbonic anhydrase 2; carbonic anhydrase B; carbonic anhydrase C; carbonic dehydratase; carbonate dehydratase II; epididymis luminal protein 76;
Chromosome8
Map Location8q22
EC Number4.2.1.1
SummaryThe protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
OrthologsView orthologs and multiple alignments for CA2

Proteins

carbonic anhydrase 2 isoform 1
Refseq ID:NP_000058
Protein GI:4557395
UniProt ID:P00918
mRNA ID:NM_000067
Length:260
RefSeq Status:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSL
DGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTP
PLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
 
carbonic anhydrase 2 isoform 2
Refseq ID:NP_001280604
Protein GI:654823808
UniProt ID:V9HW21
mRNA ID:NM_001293675
Length:159
RefSeq Status:
MVMLSTWSLMTLRTKQLHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPP
LLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
 
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